(Non)Parallel developmental pathways to vertebrate appendage reduction
- Samantha Swank,
- Thomas Sanger,
- Yoel Stuart
Abstract
Appendages have been reduced or lost hundreds of times independently
during vertebrate evolution. This suggests that selection routinely
favors appendage reduction. How often are the same developmental and
genetic pathways used during loss by independent lineages? We reviewed
the developmental and evolutionary literatures of appendage reduction in
12 genera spanning fish, reptiles, birds, and mammals. We found that
appendage reduction and loss resulted from modified gene expression in
each case but one. However, the genes for which expression was modified
were rarely shared. Our findings suggest that adaptive loss of complex
traits might proceed relatively easily through changes in gene
expression along multiple developmental pathways.10 May 2021Submitted to Ecology and Evolution 11 May 2021Submission Checks Completed
11 May 2021Assigned to Editor
18 May 2021Reviewer(s) Assigned
05 Jun 2021Review(s) Completed, Editorial Evaluation Pending
15 Jun 2021Editorial Decision: Revise Minor
31 Aug 20211st Revision Received
01 Sep 2021Submission Checks Completed
01 Sep 2021Assigned to Editor
01 Sep 2021Review(s) Completed, Editorial Evaluation Pending
07 Sep 2021Reviewer(s) Assigned
21 Sep 2021Editorial Decision: Accept