Effect of Hyperglycemia Treatment on Complications Rate after Pediatric
Cardiac Surgery: a randomized clinical trail
Abstract
Objective(s): The goal of this study was to elucidate harmful
complications of intraoperative hyperglycemia following children cardiac
surgery and benefits of insulin administration for accurate blood sugar
controlling. Design: Randomized clinical trial Setting: operating room
of shahid madani hospital Patients: 50 patients who were children under
12 years old undergoing cardiac surgery using Cardiopulmonary Bypass
(CPB). Interventions: Intraoperative insulin infusion was administered
intravenously targeting at blood sugar levels of 110-140mg/dL
Measurements and Main Results: Blood sugar and ABG were measured every
30 min during operation. The means of hospitalization and extubation
time were more in the placebo than study group (P=0.03) and (P=0.005),
respectively. However, the mean of hospitalization in the ICU ward was
not significantly between groups. Conclusions: Hyperglycemia prevalence
was lower in our study than mentioned studies in which the patients were
either given insulin or not. Hyperglycemia duration has relation with
long hospitalization time in ICU and hospital. These findings suggest
the positive effect of accurate blood sugar control on reducing
complication and hospitalization time in children undergoing cardiac
surgery.