loading page

Effects of local anesthetics (neural therapy) on pain and hand functions in patients with De Quervain tenosynovitis: A prospective randomized controlled study
  • +1
  • Hüma Bölük Şenlikci,
  • Özden Sibel Odabaşı,
  • Fatma Gülçin Ural Nazlıkul,
  • Hüseyin Nazlıkul
Hüma Bölük Şenlikci

Corresponding Author:[email protected]

Author Profile
Özden Sibel Odabaşı
Dr Nafiz Körez Sincan Devlet Hastanesi
Author Profile
Fatma Gülçin Ural Nazlıkul
Yildirim Beyazit University Faculty of Medicine
Author Profile
Hüseyin Nazlıkul
International federation of medical associations of neural therapy
Author Profile


Objective: De Quervain tenosynovitis is the most common cause of lateral wrist pain. The diagnosis can be made with the Finkelstein test when pain is provoked with wrist ulnar deviation. Conservative treatment including rest, non-steroidal anti-inflammatory medication and physical therapy is applied first, then there may be a need for corticosteroid injections, and in resistant cases, surgery. The aim of this study was to evaluate the effectiveness of neural therapy (NT) on pain and hand functions in patients with De Quervain tenosynovitis. Methods: A total of 36 patients admitted between May 2019 and March 2020 were randomly assigned to neural therapy (NT) and control groups. Hand rest and thumb spica splint were applied to all the patients, and NT interventions to the NT group only. A visual analog scale (VAS) and the Duruöz Hand index (DHI) were used to measure pain and functionality at baseline, then at 1 and 12 months after the end of the treatment. Results: The NT and control groups both showed improvements in VAS and DHI scores at 1 and 12 months compared to baseline. The VAS scores were significantly lower at both 1 and 12 months compared to baseline in the NT group. The DHI scores were lower in the NT group at 1 month, and at 12 months there was no significant difference between the two groups. No adverse effects were seen in any patient. Conclusion: NT seems to be effective in reducing pain and improving hand functions in patients with De Quervain tenosynovitis.
21 Apr 2021Submitted to International Journal of Clinical Practice
22 Apr 2021Submission Checks Completed
22 Apr 2021Assigned to Editor
01 May 2021Reviewer(s) Assigned
16 May 2021Review(s) Completed, Editorial Evaluation Pending
08 Jun 20211st Revision Received
10 Jun 2021Submission Checks Completed
10 Jun 2021Assigned to Editor
10 Jun 2021Review(s) Completed, Editorial Evaluation Pending
12 Jun 2021Reviewer(s) Assigned
25 Jun 2021Editorial Decision: Accept