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A singularly perturbed vector-bias malaria model incorporating bed-net control
  • Sanaa Salman
Sanaa Salman
Alexandria University

Corresponding Author:[email protected]

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Abstract

A malaria transmission disease model with host selectivity and Insecticide treated bed nets (ITNs), as an intervention for controlling the disease, is formulated. Since the vector is an insect, the vector time scale is much more expeditious than the host time scale. This leads to a singularly perturbed model with two distinctive intrinsic time scales, two-slow for the host and one-fast for the vector. The basic reproduction number R0 is calculated and the local stability analysis is performed at equilibria of the model when the perturbation parameter ɛ > 0. The model is analyzed when ɛ → 0 using asymptotic expansions technique. Merging bed-net control, vector-bias, and singular perturbation have a notable effect on the model dynamics. It is shown that if over %30 of humans use ITNs, malaria disease burden can be reduced. The dynamics on the slow surface indicate that the infected vectors decays very fast when ɛ = 0.001 according to the numerical simulations.
20 Apr 2021Submitted to Mathematical Methods in the Applied Sciences
21 Apr 2021Submission Checks Completed
21 Apr 2021Assigned to Editor
27 Apr 2021Reviewer(s) Assigned
02 Jun 2022Review(s) Completed, Editorial Evaluation Pending
02 Jun 2022Editorial Decision: Revise Major
03 Aug 20221st Revision Received
05 Aug 2022Submission Checks Completed
05 Aug 2022Assigned to Editor
06 Aug 2022Reviewer(s) Assigned
11 Oct 2022Review(s) Completed, Editorial Evaluation Pending
12 Oct 2022Editorial Decision: Accept
31 Oct 2022Published in Mathematical Methods in the Applied Sciences. 10.1002/mma.8822