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Breaktrough drug combination for Congenital Junctional Ectopic Tachycardia: a pediatric case report.
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  • Giovanni Di Marco,
  • Angelica De Nigris,
  • Angela Pepe,
  • Annamaria Pagano,
  • Giangiacomo Di Nardo
Giovanni Di Marco
AORN Santobono Pausilipon

Corresponding Author:[email protected]

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Angelica De Nigris
University of Campania Luigi Vanvitelli
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Angela Pepe
Univesity of Salerno
Annamaria Pagano
University of Naples “Federico II”
Giangiacomo Di Nardo
AORN Santobono Pausilipon
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Introduction: Congenital Junctional Ectopic Tachycardia (JET) is a rare tachyarrhythmia that remains difficult to manage with suboptimal control in the majority of cases. Methods: Here, we report the successful use of Ivabradine in combination with Flecainide for the therapy of congenital JET resistant to multiple antiarrhythmic agents. Results: This new drug combination was effective in completely suppressing JET . Conclusion: Ivabradine in combination with Flecainide may be considered a new therapeutic strategy of congenital JET with satisfactory efficacy/tolerability ratio in patients resistant to conventional drug combinations.