The relationship between mixed vaginitis in late pregnancy and adverse
pregnancy outcomes：a cross-sectional study.
Objective：To clarify the epidemiological characteristics, risk factors,
clinical symptoms and signs, laboratory features, and pregnancy outcomes
of women with mixed vaginitis during late pregnancy. Methods：The study
population consisted of 1103 women in late pregnancy who attended the
Tianjin Medical University General Hospital from November 2019 to
September 2020. Results：The incidence rate of mixed vaginitis during
late pregnancy is 4.1% (44/1075). The independent risk factors for
women with mixed vaginitis in late pregnancy are a positive glucose
tolerance test (OR = 2.697, 95% CI 1.293-5.625) and a history of
vaginitis during pregnancy (OR = 2.276, 95% CI 1.030-5.032). Compared
with women with single vaginitis, women with mixed vaginitis only have
statistically significant differences in the yellow discharge (77.3%
vs. 58.9%) and malodor (40.9% vs. 22.7%) (P＜0.05), so they are
easily confused with single vaginitis in clinical symptoms and signs.
Compared with women with single vaginitis, women with mixed vaginitis
have a significant difference in pH＞4.5 (72.7% vs. 36.2%) and
WBC＞10/hpf (81.8% vs. 38%) in laboratory examination(P＜0.05).
Therefore, laboratory diagnosis is the main method to distinguish single
and mixed vaginitis. Compared with women without vaginitis, women with
mixed vaginitis have an increased incidence of postpartum puerperal
infections (6.8% vs. 1%; P＜0.05). Conclusions：Mixed vaginitis in
late pregnancy leads to an increased incidence of puerperal infections.
Therefore, more attention should be paid to the early intervention of
mixed vaginitis during pregnancy to prevent adverse pregnancy outcomes.