Levothyroxine-associated lichenoid drug eruption: A case report and
review of levothyroxine-induced adverse reactions
Abstract
Levothyroxine (LT4) is frequently used as thyroid hormone replacement to
treat hypothyroidism. Adverse skin reactions are not common. Lichenoid
drug eruption is a one such medication-related reaction. the lesion
morphology and pathology mimic lichen planus. The current case describes
a 47-year-old man who presented to us with a diffuse
levothyroxine-induced lichenoid drug eruption. The Naranjo adverse drug
reaction probability assessment score suggested this was likely an ADR
to levothyroxine. The eruption resolved after discontinuation of the
medication. We also reviewed the literature on levothyroxine-associated
adverse events.