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Clinical, laboratory and chest computed tomography aspects of hospitalized patients with COVID-19 in northern Iran
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  • ali sharifpour,
  • sepideh Safanavaei,
  • Rabeeh Tabaripour ,
  • fatemeh Taghizadeh,
  • maryam nakhaei,
  • atikeh abadi,
  • Mahdi Fakhar,
  • Elham Sadat Banimostafavi ,
  • Sayed Rasooli,
  • Masoud aliyali,
  • Siavash abedi,
  • Hossein Hossein Mehravaran
ali sharifpour
Mazandaran University of Medical Sciences Faculty of Medicine
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sepideh Safanavaei
Mazandaran University of Medical Sciences Faculty of Medicine
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Rabeeh Tabaripour
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fatemeh Taghizadeh
Mazandaran University of Medical Sciences
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maryam nakhaei
Mazandaran University of Medical Sciences Faculty of Medicine
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atikeh abadi
Mazandaran University of Medical Sciences Faculty of Medicine
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Mahdi Fakhar
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Elham Sadat Banimostafavi
Mazandaran University of Medical Sciences Faculty of Medicine
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Sayed Rasooli
Mazandaran University of Medical Sciences Faculty of Medicine
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Masoud aliyali
Mazandaran University of Medical Sciences Faculty of Medicine
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Siavash abedi
Mazandaran University of Medical Sciences Faculty of Medicine
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Hossein Hossein Mehravaran
Mazandaran University of Medical Sciences Faculty of Medicine
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Abstract

The clinical symptoms, blood laboratory data, O2 saturation and high resolution computed tomography (HRCT) findings are critical factors in diagnosis of COVID-19 infection. In this study, 105 hospitalized patients suspected of having COVID-19 were evaluated. Finally, the data of 83 confirmed cases by HRCT and RT-PCR were analyzed. 61.40% of the patients had a comorbidity disease. 89.20% had fever, 92.00% cough, 91.40% dyspnea. Abnormal CRP seen in 77.80% of the patients following by 66.70% lymphopenia, and 60.30% neutrophilia. Also, ALP (abnormal vs. normal) and score of HRCT assessment variables had a significant effect on the positiveness of HRCT findings. 87.95% had abnormal HRCT with 41% bilateral multilobar patchy ground glass opacity (GGO). Moreover, there was a statistically significant association between level of O2 saturation and HRCT results. Our findings showed that male patients with middle age and comorbidity disease were more susceptible to the COVID-19 infection. Additionally, clinical features, blood laboratory findings, O2 saturation and HRCT findings are critical factors in prognosis of COVID-19 infection.