SEVERE SINUS BRADYCARDIA SECONDARY TO THE USE OF INTRAVENOUS STEROIDS.
High-dose glucocorticoids are commonly used for a wide variety of
childhood diseases. They are known to cause several side-effects by oral
administration; nonetheless, side-effects associated with intravenous
bolus are not well known1. Whereas a rise in blood pressure is a
well-known side-effect of corticosteroid treatment, sinus bradycardia
has been reported as another adverse effect of high-dose glucocorticoid
therapy2. This effect mainly occurs in adults and few cases have been
described in children. We report two cases of sinus bradycardia due to
intravenous methylprednisolone administration in paediatric oncology
patients and the approach we adopted for their resolution.