New understanding of TFEB and autophagy in the development of
Endometriosis is a benign gynecologic disease, but it is similar in
behavior to malignant tumors, so it is called “benign gynecologic
cancer”. At present, its pathogenesis is not fully understand.
Autophagy has been the focus of recent research on various diseases,
which has also been shown to have regulatory abnormalities in
endometriosis. TFEB is a key regulator of autophagy. The upstream signal
molecules and downstream effector proteins of TFEB have abnormal
expression in endometriosis. So TFEB may be an effective target for
controlling the development of endometriosis. This review aims to
discuss the relationship between TFEB and endometriosis.