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Diagnostic Value of Lung Ultrasonography in Children with COVID-19
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  • Mina Gharibzadeh Hızal,
  • Kubra Aykac,
  • Burcu Ceylan Cura Yayla,
  • Arzu Yılmaz,
  • Gulsum Iclal Bayhan,
  • Demey Altun,
  • Habibp Eser Akkaya,
  • Aysegul Nese Citak Kurt,
  • Jale Karakaya,
  • Yasemin Ozsurekci,
  • Mehmet Ceyhan
Mina Gharibzadeh Hızal
Hacettepe University

Corresponding Author:minahizal@outlook.com

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Kubra Aykac
Sağlık Bakanlığı Ankara Eğitim ve Araştırma Hastanesi
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Burcu Ceylan Cura Yayla
Saglik Bakanligi Ankara Egitim ve Arastirma Hastanesi
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Arzu Yılmaz
Sağlık Bakanlığı Ankara Eğitim ve Araştırma Hastanesi
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Gulsum Iclal Bayhan
Yildirim Beyazit University Faculty of Medicine
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Demey Altun
Ufuk University
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Habibp Eser Akkaya
Sağlık Bakanlığı Ankara Eğitim ve Araştırma Hastanesi
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Aysegul Nese Citak Kurt
Yildirim Beyazit University
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Jale Karakaya
Hacettepe University
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Yasemin Ozsurekci
Hacettepe University Faculty of Medicine
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Mehmet Ceyhan
Hacettepe University, Faculty of Medicine,
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Background: Lung ultrasound (LUS) has been successfully used in the diagnosis of different pulmonary diseases. Present study design to determine the diagnostic value of LUS in the evaluation of children with COVID-19, and to compare chest X-ray and LUS results with tomography (CT).   Method and objectives: In this prospective multi-center study, 40 children with confirmed COVID-19 were included. LUS was performed to all patients at admission. The chest X‐ray and CT were performed according to the decision of the primary physicians. LUS results were compared with chest X-ray and CT. The sensitivity and specificity and diagnostic performance was determined. Results: Of the 40 children median (range) was 10.5 (0.4-17.8) years. Chest X-ray and LUS were performed on all and chest CT was performed on 28 (70%) patients at the time of diagnosis. Sixteen (40%) patients had no apparent chest CT abnormalities suggestive of COVID-19, whereas 12 (30%) had abnormalities. LUS confirmed the diagnosis of pulmonary involvement in 10 out of 12 patients with positive CT findings. LUS demonstrated normal lung patterns among 15 patients out of 16 who had normal CT features. The sensitivity identified by the chest X-ray and LUS tests was comparedand statistically significantly different (p=0.016). Chest X-ray displayed false-negative results for pulmonary involvement in 75% whereas for LUS it was 16.7%. Conclusions: LUS might be a useful tool in the diagnostic steps of children with COVID-19. A reduction in chest CT assessments may be possible when LUS is used in the initial diagnostic steps for these children.
27 Jun 2020Submitted to Pediatric Pulmonology
27 Jun 2020Submission Checks Completed
27 Jun 2020Assigned to Editor
29 Jun 2020Reviewer(s) Assigned
15 Aug 2020Review(s) Completed, Editorial Evaluation Pending
15 Aug 2020Editorial Decision: Revise Major
26 Aug 20201st Revision Received
26 Aug 2020Assigned to Editor
26 Aug 2020Reviewer(s) Assigned
26 Aug 2020Submission Checks Completed
10 Sep 2020Review(s) Completed, Editorial Evaluation Pending
10 Sep 2020Editorial Decision: Revise Minor
10 Sep 20202nd Revision Received
11 Sep 2020Submission Checks Completed
11 Sep 2020Assigned to Editor
11 Sep 2020Reviewer(s) Assigned
28 Sep 2020Review(s) Completed, Editorial Evaluation Pending
09 Oct 2020Editorial Decision: Accept