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  • +12
  • Desiree Caselli,
  • Antonella Colombini,
  • Daniele Zama,
  • Elio Castagnola,
  • Paola Muggeo,
  • Milena La Spina,
  • Katia Perruccio,
  • Raffaela De Santis,
  • Francesca Carraro,
  • Federico Mercolini,
  • Mariagrazia Petris,
  • Daniela Onofrillo,
  • Rosamaria Mura,
  • Valentina Barretta,
  • Simone Cesaro
Desiree Caselli
1. Infectious Diseases, Giovanni XXIII Children Hospital, Azienda Ospedaliero Universitaria Consorziale Policlinico

Corresponding Author:desiree.caselli@policlinico.ba.it

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Antonella Colombini
MBBM Foundation, University of Milano-Bicocca, Monza, Italy
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Daniele Zama
Department of Pediatrics, Pediatric Oncology and Haematology Unit "Lalla Seràgnoli", Sant' Orsola Malpighi Hospital, University of Bologna
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Elio Castagnola
Infectious Diseases Unit, IRCCS Istituto Giannina Gaslini, Genova
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Paola Muggeo
University Hospital of Policlinico Bari
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Milena La Spina
Policlinico di Catania
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Katia Perruccio
Pediatric Oncology and Hematology Section
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Raffaela De Santis
Unit of Pediatrics
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Francesca Carraro
Pediatric Onco-Hematology, Stem Cell Transplantation and Cellular Therapy Division, AOU Città della Salute e della Scienza, Regina Margherita Childrens Hospital
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Federico Mercolini
Azienda Ospedaliera di Bolzano
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Mariagrazia Petris
3. Pediatric Hematology-Oncology
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Daniela Onofrillo
Santo Spirito Hospital,
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Rosamaria Mura
Paediatric Haematology-Oncology, Ospedale Pediatrico Microcitemico, Cagliari, Italy
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Valentina Barretta
Pediatric Hematology-Oncology, Azienda Ospedaliera Universitaria Integrata
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Simone Cesaro
Pediatric Hematology and Oncology Unit, Department of Pediatrics, Azienda Ospedaliera Universitaria Integrata, Verona
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Carbapenemase-producing Enterobacteriaceae (CPE) , multidrug resistant (MDR) threatens children undergoing chemotherapy. A previous survey reported increase of bloodstream infections and colonization in a 2 year-observation time. To test the efficacy of the measures put in place , a second survey was performed. Data were collected from 13 Italian pediatric cancer centers of AIEOP network. The colonization rate per 1000 hospitalizations days was 0.5 (0.37-0.65) not different from the 0.48 rate (0.36-0.63) observed previously .Yet the 0.12 rate of bacteriemia (0.07-0.21) compared favorably with the 0.42 (0.31-0.57) observed. The awareness of colonization status allowed reducing CPE related morbidity and mortality.