Infant T-Cell Acute Lymphoblastic Leukemia Presenting with Macrocephaly:
A Case Report
Abstract
A 6.5-month-old girl presented to a pediatrician for a second opinion
regarding worsening macrocephaly and developmental regression. She then
underwent neurosurgical evaluation. Rapid-sequence magnetic resonance
imaging was significant for benign enlargement of the subarachnoid space
of infancy. A complete blood count was significant for 33% blasts in
the peripheral blood. Flow cytometry of the peripheral blood established
a diagnosis of T-cell Acute Lymphoblastic Leukemia (ALL). T-cell ALL has
been rarely reported and our patient’s presentation with macrocephaly is
particularly unique.