Ibuprofen potential addition to COVID-19 early management protocols:
could it be superior to paracetamol and hydroxychloroquine?
The pathogenesis of Coronavirus disease 2019 is still obscure, indeed
it’s only few months since it has been first reported on December 2019,
yet the need for exploration of possible mechanisms, suggestion of new
drugs should never be delayed. In this communication, the author
proposes an integrated pathophysiological as well as pharmacological
COVID-19 approach to recommend using anti-inflammatory drugs, other than
glucocorticoids, suggesting ibuprofen as an example, to be added to his
recently published suggested COVID-19 early management protocol. A
possible explanation for the potential failure of hydroxychloroquine for
COVID-19 is also explained according to the suggested concept. The
author is fully aware of the ibuprofen contradictory hypothesis; as
discussed and argued against in this report.