Better than Expected Prognosis of Minimal Tracheal Invasion in Well
Differentiated thyroid carcinoma
Background: The aim of this study was to compare outcomes of patients
with minimal tracheal invasion undergoing shave resection to other forms
of ETE in lieu of the new American Joint Committee on Cancer (AJCC)
staging. Methods: All patients diagnosed with well differentiated
thyroid cancer (WDTC) and ETE were analyzed. Structural recurrence was
measured and compared between various forms of ETE. Results: A total of
132 patients were included in the study. Twenty-seven patients (20.4%)
had strap muscle invasion, twenty-two patients (16.7%) had minimal
tracheal invasion and 83 patients (62.9%) had other forms of ETE.
Kaplan-Meier models for structural recurrence revealed that when
combining T3b patients with T4a shave patients and comparing them to
other T4a patients, the former performed better than the latter (p=0.028
for all ages; p= 0.021; for patients >55 years).
Conclusions: Patients with minimal tracheal may be more correctly staged
as T3b rather than T4a.