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PLOS Science Wednesday: Hi reddit, we’re Nick, Jenna and Fumiaki, and we contributed research to the new PLOS Medicine special issue on diabetes prevention – Ask Us Anything!
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Hi Reddit, My name is Nick Wareham and I am Director of the MRC Epidemiology Unit at the University of Cambridge. My research focuses on the genetic and environmental determinants of type 2 diabetes and the translation of epidemiological knowledge into preventive action. I also served as a guest editor on the PLOS Medicine special issue on Diabetes Prevention. I also wrote the editorial entitled “ ‘The Clinical and Public Health Challenges of Diabetes Prevention: A Search for Sustainable Solutions” in which we discuss how diabetes is driven by rapid economic development and how attempts to deal with a public health problem by clinical approaches to prevention will be unaffordable and unsustainable in many countries. We focus on the need to develop effective and sustainable public health interventions for the prevention of type 2 diabetes that can be implemented in both resource-rich and resource-poor health care systems. I am joined by Fumiaki Imamura and Jenna Panter, two scientists at the MRC Epidemiology Unit at the University of Cambridge, who also contributed research to the Diabetes Prevention issue of PLOS Medicine. Jenna is a Senior Research Associate in the MRC Epidemiology Unit. Her research focuses on examining patterns and determinants of change in physical activity and evaluating environmental and policy interventions to promote activity. Jenna recently published an article titled ‘Cycling and Diabetes Prevention: Practice-Based Evidence for Public Health Action’ in PLOS Medicine in which the authors discuss the findings from a linked paper by Rasmussen and colleagues on changes in cycling and risk of developing type 2 diabetes. In the article, the authors highlight the need to conduct rigorous evaluations of interventions to promote physical activity which will provide evidence about how researchers can create a genuinely population-based public health strategy for the prevention of diabetes and other chronic diseases. Fumiaki is a Senior Investigator Scientist at the MRC Epidemiology Unit. His research focuses on effects of dietary components and behaviours with a risk of developing type 2 diabetes. Fumiaki recently published a study titled “Effects of Saturated Fat, Polyunsaturated Fat, Monounsaturated Fat, and Carbohydrate on Glucose-Insulin Homeostasis: A Systematic Review and Meta-analysis of Randomised Controlled Feeding Trials” in PLOS Medicine. I am also a co-author of a study published by the EPIC-InterAct Study in the PLOS Medicine, ““Association of Plasma Phospholipid n-3 and n-6 Polyunsaturated Fatty Acids with Type 2 Diabetes: The EPIC-InterAct Case-Cohort Study”. In the two studies based on published trials and the Europe-wide observational investigation, respectively, Fumiaki and colleagues indicate that fat commonly present in vegetable oils is good to reduce the burden of type 2 diabetes in many countries. We will be answering your questions at 1pm ET – Ask Us Anything! Don’t forget to follow us on Twitter @JennaPanter, @fumimamu and @mrc_epid.