We identified anomalously high sea surface temperature (SST) events during the 40-year period 1980–2019 near the Punta Lavapié upwelling center in the Chile-Peru Current System (CPCS). Annual distributions of SST anomalies, taken from fifth generation European Centre for Medium-Range Weather Forecasts (ECMWF) reanalysis (ERA5), by season and month indicated that warm SST anomalies were most likely to occur in the austral summer (December through February). At the time of peak warming before the strongest 37 events, we estimated a surface mixed-layer anomaly heat budget with the mean rate of total SST anomaly change and mean rate of SST anomaly change from the net surface heat flux anomaly. The mean net surface heat flux anomaly over the 37 historical warming events was too small to account for most of the maximum rate of anomalous warming. We propose that the weakened surface wind stress observed at the times of maximum warming could amplify the effect of the positive summertime net surface heat flux through mixed-layer shoaling or reduce cold water entering the mixed-layer via entrainment at the base of the surface mixed-layer. This interpretation is based on similarities between the composite mean anomalies of wind stress at the time of peak warming preceding these 37 events in the CPCS and the anomaly fields during previous studies of weak wind events in the California Current System (CCS). Future studies should further investigate the behavior and influence of the surface wind stress and mixed-layer evolution during warm SST anomaly events.