The East China Sea (ECS) seasonally receives a high organic input due to the terrestrial organic matter influx, which is controlled by the East Asian Summer Monsoon (EASM), and from increased productivity due to upwelling of the subsurface Kuroshio Current (KC). Changes in benthic foraminiferal assemblage composition in combination with paleoceanographic proxy data (CaCO3 (%), TOC (%), δ13Cpf, and δ18Obf) are used to reconstruct bottom water oxygenation and organic export flux variability over the last 400 kyr in the ECS. Multivariate analyses of benthic foraminiferal census data identified six biofacies characteristic of varying environmental conditions. These results suggest enhanced EASM precipitation and KC upwelling directly influenced bottom water oxygen content and organic export flux in the ECS. The ECS bottom water was suboxic from MIS (Marine Isotope Stage) 11 to 8; suboxic to dysoxic between MIS 7 and 6, strongly dysoxic between mid-MIS 5 and 4, and exhibited high variability between MIS 3 and 1. Spectral analysis of abundance variations of the representative genera Quinqueloculina (oxic), Bulimina (suboxic), and Globobulimina (dysoxic) reveals a robust 23 kyr signal, which we attribute to precessionally-paced changes in surface productivity and bottom water oxygenation related to EASM and KC variability over the past 400 kyr.