Hoxb8 MC activation correlates better with sIgE than
SPT.
To better understand if the data we generated using Hoxb8 MC passively
sensitized with serum samples correlate with results from allergy
diagnosis tests routinely performed in clinics, we performed linear
regression analyses between the maximal activation of Hoxb8 MCs achieved
upon allergen stimulation and either SPT or sIgE measurements. Only a
weak (r=0.3), yet statistically significant, relationship between the
Hoxb8 MC activation and SPT results was found (Fig. 3a ).
Furthermore, there was a strong but imperfect correlation with sIgE
measurements against peanut extract (r=0.91) and Ara h2 (r=0.81)
(Fig. 3b-d ).