AUTHOR CONTRIBUTIONS
Conceptualisation, J.S.C.; investigation, G.R. and J.N.; sample
collection, C.P.O.; writing of the original draft preparation, G.R. and
J.N.; review and editing, C.P.O.; V.G.; J.A.M.P., R.P. and J.S.C.;
Visualization, J.A.M.P., R.P. and J.S.C.; Supervision: J. S. C., R. P.,
and J. A. M. P.; Funding Acquisition: J.S.C. All authors have read and
agreed to the published version of the manuscript. All authors confirm
that they have full access to all data in the study and accept the
responsibility to submit the manuscript for publication.
ACKNOWLEDGEMENTS
This work was supported by FCT-Fundação para a Ciência e a Tecnologia
through the CQM Base Fund-UIDB/00674/2020 and Programmatic
Fund-UIDP/00674/2020; and by ARDITI-Agência Regional para o
Desenvolvimento da Investigação Tecnologia e Inovação through the
project M1420-01-0145-FEDER-000005-Centro de Química da Madeira-CQM+
(Madeira 14-20 Program). Giulia Riccio was supported by a PhD
scholarship given by Università Cattolica del Sacro Cuore, 00168 Rome,
Italy.
The authors would like to thank all staff members at SESARAM, EPE-RAM
and Dr. Nélio Mendonça Hospital for their help in conducting this
research. We would also like to thank all the donors who participated in
this study. The authors also acknowledge financial support from the
Fundação para a Ciência e Tecnologia and Madeira 14-2020 program to the
Portuguese Mass Spectrometry Network through the PROEQUIPRAM program
M14-20 M1420-01-0145-FEDER-000008. Jorge A. M. Pereira was supported by
a research contract given by Centro de Química da Madeira and
Universidade da Madeira.