Notes
Contributors : Feng Jiang, Xiaohu Han, Yongxiang Zhao and Zeliang Chen conceptualized the initial hypothesis and conceived and designed the study. Feng Jiang, Xiaohu Han, Ya Wen, Yao Chen, Hua Deng, Qing Xin, Yudan Bi and Yicheng Zhou carried out the sample collection and the molecular testing. Yongxiang Zhao, Yao Chen, Hua Deng and Ya Wen collected and sorted out the data. Ruihao Peng edited the table. Qijun Chen, Xiaohu Han, Ruihao Peng conducted literature search and participated in the writing part. Xiaohu Han, Ruihao Peng and Zeliang Chen did the statistical analysis and wrote the first draft of the manuscript. Qijun Chen and Zeliang Chen revised the manuscript. All authors contributed substantially to data acquisition and interpretation, and revision and editing of the manuscript. The Sixth People’s Hospital of Dandong City provided patient samples and related data for this project.
Funding : This study was supported by the Science and Technology Partnership Program,Ministry of Science and Technology of China (KY201901014), Qijun Chen, Zeliang Chen Xiaohu Han,Feng Jiang received funding from the project; this study is also funded by the National Science and Technology Major Project (2018ZX10101002), Xiaohu Han, Zeliang Chen received funding from the project.
Availability of data and materials : All data and codes supporting the findings of this study are derived from open databases.
Ethical approval : No.01(2022)of The Sixth People’s Hospital of Dandong City.
Declaration of competing interest : The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.